Your doctor may need to give you a lower dose of zolpidem. You can also report side effects directly via the Yellow Card Scheme at: Retrieved April 14, To prevent withdrawal reactions, your doctor may reduce your dose gradually. Taking zolpidem with other drugs that make you sleepy or slow your breathing can cause dangerous or life-threatening side effects. Feeling drowsy, confused, sleeping deeply and possibly falling into a coma. Consult your doctor or pharmacist for ways to improve your sleep without medication, such as avoiding caffeine and alcohol close to bedtime , avoiding daytime naps, and going to bed at the same time each night.
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Zolpidem may also cause other side effects. If these effects are mild, they may go away within a few days or a couple of weeks. Call your doctor right away if you have serious side effects. Serious side effects and their symptoms can include the following:. Our goal is to provide you with the most relevant and current information. However, because drugs affect each person differently, we cannot guarantee that this information includes all possible side effects. This information is not a substitute for medical advice.
Always discuss possible side effects with a healthcare provider who knows your medical history. Zolpidem oral tablet can interact with other medications, vitamins, or herbs you may be taking. An interaction is when a substance changes the way a drug works. This can be harmful or prevent the drug from working well. To help avoid interactions, your doctor should manage all of your medications carefully.
Taking zolpidem with certain medications raises your risk of side effects. This is because zolpidem and these other medications can cause the same side effects. As a result, these side effects can be increased. Examples of these drugs include:. Taking zolpidem with certain medications raises your risk of side effects from zolpidem. This is because the amount of zolpidem in your body may be increased. When zolpidem is used with certain drugs, it may not work as well to treat your condition.
This is because the amount of zolpidem in your body may be decreased. However, because drugs interact differently in each person, we cannot guarantee that this information includes all possible interactions. Always speak with your healthcare provider about possible interactions with all prescription drugs, vitamins, herbs and supplements, and over-the-counter drugs that you are taking. If you have an allergic reaction, call your doctor or local poison control center right away.
If your symptoms are severe, call or go to the nearest emergency room. Taking it again could be fatal cause death. Eating food with zolpidem may make the drug take longer to work. You should take this drug on an empty stomach. Drinking alcohol can increase your risk of sedation and drowsiness from zolpidem. If you drink alcohol, talk to your doctor. You may need to be monitored more closely for side effects.
For people with depression: This drug may make your symptoms of depression worse. Ask your doctor if this drug is safe for you. For people with lung or breathing problems: This drug may slow your breathing or make it shallow. This can decrease the amount of oxygen in your blood. If you have trouble breathing, you may already have lower oxygen levels. For people with myasthenia gravis: If you have myasthenia gravis, you may already have lower oxygen levels.
For people with sleep apnea: If you have sleep apnea, you may already have lower oxygen levels. For people with liver disease: If you have liver problems or a history of liver disease, you may not be able to process this drug well. This may increase the levels of the drug in your body and cause more side effects. It may also cause a serious condition called hepatic encephalopathy. With this condition, the poor function of your liver causes problems with the way your brain works.
Symptoms can include being confused, forgetting things, and slurring your speech. If you have severe liver damage, you should not use zolpidem. Zolpidem is a category C pregnancy drug. That means two things:. This drug should only be used if the potential benefit justifies the potential risk to the pregnancy. Call your doctor right away if you become pregnant while taking this drug. For women who are breastfeeding: Zolpidem may pass into breast milk and cause side effects in a child who is breastfed.
Talk to your doctor about breastfeeding your child. You may need to decide whether to stop breastfeeding or stop taking this medication. The liver of an older adult may not work as well as it used to. This can cause your body to process drugs more slowly. As a result, more of a drug stays in your body for a longer time. This raises your risk of side effects, such as sedation and decreased alertness.
You may also be more sensitive to these effects. This dosage information is for zolpidem oral tablets. All possible dosages and drug forms may not be included here. Your dosage, drug form, and how often you take the drug will depend on:. This raises your risk of side effects. Your doctor may start you on a lowered dosage or a different treatment schedule. This can help keep levels of this drug from building up too much in your body.
Ambien, Zolpimist, Edluar, and generic immediate-release oral tablets: Ambien CR and generic extended-release oral tablets only: Take it when you have trouble falling back to sleep after waking in the middle of the night. What is a Patient Information Leaflet and why is it useful? You may need to read it again. If you have any further questions, ask your doctor or pharmacist. This medicine has been prescribed for you only. Do not pass it on to others. It may harm them, even if their signs of illness are the same as yours.
If you get any of the side effects, talk to your doctor or pharmacist. Your doctor may have given you this medicine before from another company. It may have looked slightly different. However, either brand will have the same effect. What is in this leaflet: What zolpidem is and what it is used for The name of your medicine is Zolpidem 5mg or 10mg Tablets called zolpidem throughout this leaflet. Zolpidem is used to treat sleep problems in adults such as: Difficulty falling asleep Waking in the middle of the night Zolpidem is used for temporary sleep problems.
What you need to know before you take zolpidem Do not take zolpidem: If you are allergic hypersensitive to zolpidem tartrate or any of the other ingredients of this medicine listed in section 6. Signs of an allergic reaction include: If you have a problem where you stop breathing for short periods at night sleep apnoea. If you have a problem that causes severe muscle weakness myasthenia gravis.
If you have breathing difficulties hypoventilate. If you have severe liver problems. If you are under the age of If you have a severe mental illness. Warnings and precautions Check with your doctor or pharmacist before taking zolpidem: If your lungs do not work properly. Your doctor may need to give you a lower dose of zolpidem. If you have a history of drug or alcohol abuse. If you are or have been depressed.
If you do not feel you will ever be able to stop taking zolpidem or other medicines used to treat sleep problems. You take this medicine less than 8 hours before performing activities that require your alertness. You take a higher dose than recommended. You take zolpidem while you are already taking other central nervous system depressants or other medicines that increase zolpidem in your blood, or while drinking alcohol, or while taking illicit substances.
Take the single intake immediately at bedtime. Do not take another dose during the same night. Other medicines and zolpidem Please tell your doctor or pharmacist if you are taking, have recently taken or might take any other medicines. Tell your doctor if you are taking any of the following medicines: Zolpidem may increase the effect of the following medicines: While taking zolpidem with the following medicines, drowsiness and next-day psychomotor impairment effects, including impaired driving ability, may be increased: Medicines for mental problems antipsychotics Medicines for depression such as sertraline Medicines for epilepsy anticonvulsants Medicines used in surgery anaesthetics Medicines to calm or reduce anxiety or for sleep problems hypnotics Medicines for hay fever, rashes or other allergies that can make you sleepy sedative antihistamines such as chlorphenamine or promethazine Some medicines for moderate to severe pain narcotic analgesics While taking zolpidem with antidepressants including bupropion, desipramine, fluoxetine, sertraline and venlafaxine, you may see things that are not real hallucinations.
Risks from concomitant use with opioids Concomitant use of zolpidem and opioids strong pain killers, medicines for substitution therapy and some cough medicines increases the risk of drowsiness, difficulties in breathing respiratory depression , coma and may be life-threatening. Some medicines for fungal infections such as ketaconazole The following medicines can make zolpidem work less well: Rifampicin an antibiotic — for infections.
Taking Zolpidem with food and drink Do not drink alcohol while you are taking zolpidem. Alcohol can increase the effects of zolpidem and make you sleep very deeply so that you do not breathe properly or have difficulty waking. Pregnancy and breast-feeding Talk to your doctor before taking this medicine if you are pregnant, might become pregnant, or think you may be pregnant. Do not take zolpidem if you are in the last 3 months of pregnancy or during labour because it may be harmful to your baby.
If your doctor feels it is necessary for you to keep using this medicine your baby may be born with breathing difficulties, limp or weak muscles, a low body temperature hypothermia and may have withdrawal symptoms. Do not take zolpidem if you are breast-feeding or planning to breast-feed. Driving and using machines On the day after taking zolpidem, do not drive or use machinery or tools if you feel sleepy, dizzy or confused.
On the day after taking zolpidem as with other hypnotic medicines , you should be aware that: Zolpidem contains lactose This is a type of sugar. How to take zolpidem Always take zolpidem exactly as your doctor has told you. Taking this medicine The recommended dose per 24 hours is 10mg of zolpidem. Zolpidem should be taken: Swallow the tablet whole with a drink of water. Treatment should not normally continue beyond 4 weeks.
Do not exceed 10mg per 24 hours. Adults The recommended dose per 24 hours is one 10mg tablet or two 5mg tablets just before bedtime. Elderly or frail people The usual dose is one 5mg tablet just before bedtime. Patients with liver problems The usual starting dose is one 5mg tablet just before bedtime. Children and adolescent Do not give this medicine to children under the age of Blood Tests Zolpidem can change the levels of liver enzymes shown up in blood tests.
This can mean that your liver is not working properly. If you are going to have a blood test, it is important to tell your doctor that you are taking Zolpidem. If you take more zolpidem than you should If you take more zolpidem than you should, tell a doctor or go to a hospital casualty department straight away. Taking too much zolpidem can be very dangerous. The following effects may happen: Feeling drowsy, confused, sleeping deeply and possibly falling into a coma.
If you forget to take zolpidem Zolpidem must only be taken at bedtime. If you stop taking zolpidem Keep taking zolpidem until your doctor tells you to stop. See a doctor straight away if you get any of the following effects: Feeling anxious, shaky, irritable, agitated, or confused Feeling restless Headache Limp or weak muscles A lower level of awareness and problems with focusing or concentrating Nightmares, seeing or hearing things that are not real hallucinations Being more sensitive to light, noise and touch than normal Relaxed grip on reality Numbness and tingling in your hands and feet Aching muscles Changes in your behaviour Fits seizures.
Possible side effects Like all medicines, Zolpidem can cause side effects, although not everybody gets them. Stop taking zolpidem and see a doctor or go to a hospital straight away if: You get swelling of the hands, feet, ankles, face, lips or throat which may cause difficulty in swallowing or breathing. You could also notice an itchy, lumpy rash hives or nettle rash urticaria.
This may mean you are having an allergic reaction to zolpidem tablets. Tell your doctor or pharmacist if any of the following side effects get serious or lasts longer than a few days: Common side effects affects less than 1 in every 10 people Feeling tired or agitated Feeling sick nausea or being sick vomiting Abdominal pain Respiratory infection Diarrhoea Feeling sleepy, drowsy or confused Sleeping problems Headache Feeling dizzy Poor memory since taking zolpidem amnesia Seeing or hearing things that are not real hallucinations Nightmares Feeling irritable Back pain Uncommon side effects affects less than 1 in every people Confusion or irritability Unusual skin sensations such as numbness, tingling, pricking, burning or creeping on the skin paraesthesia Tremor Double vision Blurred vision Changes in appetite or behaviour concerning appetite Muscle pain Muscle spasms Very rare side effects affects less than 1 in every 10, people Any changes in vision, in particular loss of vision.
Itchy, lumpy rash urticaria Excessive sweating Slower breathing respiratory depression Falling over Limp or weak muscles Sleep walking Zolpidem can change the levels of liver enzymes shown up in blood tests. You have discolouration of the skin or eyes, pain in the abdomen stomach or a bloated feeling, severe itching, pale or bloody stools, extreme weakness, nausea or loss of appetite. This could be caused by an infection or injury to the liver An illness where removal of bile from the liver is blocked cholestasis.
Reporting of side effects If you get any side effects, talk to your doctor, pharmacist or nurse. By reporting side effects you can help provide more information on the safety of this medicine. How to store zolpidem Keep this medicine in a safe place where children cannot see or reach it. Contents of the pack and other information What Zolpidem 5mg and 10mg Tablets contain Each 5mg tablet contains 5mg of zolpidem tartrate as the active substance.
Each 10mg tablet contains 10mg zolpidem tartrate as the active substance. What Zolpidem 5mg and 10mg Tablets looks like and contents of the pack Zolpidem 5mg Tablets are round, white, film-coated tablets. Zolpidem 5mg Tablets are supplied in cartons of 28 tablets. Zolpidem 10mg Tablets are supplied in cartons of 28 tablets. Delpharm Dijon 6 Boulevard.
Company contact details Zentiva.